Mirica® - Palmitoylethanolamide (PEA) and Luteolin & Sunflower Lecthin 630mg
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What is PEA?
Palmitoylethanolamide (PEA) is a biologically active, endogenous lipid that is widely distributed throughout the body's tissues and is synthesized on demand. (Gabrielsson 2016) It was first isolated in 1957 as an anti-inflammatory component in egg yolks and is found in many foods. PEA has been studied extensively for its anti-inflammatory, neuroprotective and analgesic properties since the 1970's.* (Hesselink 2013)
PEA plays a key role in maintaining homeostasis by regulating many physiological reactions associated with pain and inflammation. Some chronic conditions can deplete PEA, resulting in a hyper-immune response involving glial, microglial and mast cells. Excessive activation of these satellite, non-neuronal cells has been shown to maintain inflammation and result in neurodegeneration. PEA reduces excessive activation of these cells and decreases neuron loss.* (Raso 2014)
In a recent meta-analysis of PEA involving a total of 1484 chronic pain patients, those taking PEA reported pain levels an average of 2.7 points lower than the control groups after 60 days.* (Paladini 2016)