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Entity Health - MetaboliX Plus, NAD Supplment, 60 Capsules

SKU ENT_8068

Our human body is made up of trillions of cells. They are the basic building blocks of life. Cells have specific tasks to perform and they work together to enable the body to meet its basic needs. These cellular processes require energy to function. However, as we age, cellular energy production in our body decreases1.


Nicotinamide adenine dinucleotide (NAD+) is a co-enzyme that is present naturally in every cell of our body and is essential to life. It is known as the molecule of youth due to its role in cellular energy production and its ability to regulate the genes of aging1. Unfortunately, as we grow older, the NAD+ levels in our body decline1.
MetaboliX® Plus contains nicotinamide which is a precursor of NAD+ to boost the NAD+ cellular levels in the body. Daily supplementation of MetaboliX® Plus combats the ravages of aging!


Mitochondria are powerhouses of our cells. They are empowered by NAD+ in the production of cellular energy for the sustenance of life. As the level of NAD+ declines with age, mitochondria function is impaired which results in reduced amount of surviving healthy mitochondria2. This vicious cycle of the depletion of mitochondria which results in metabolic energy deficiency is evident in the physical symptoms of aging such as chronic fatigue and weakness. NAD+ is crucial in the maintenance of functional mitochondria in preserving cellular energy reserve to ensure the body to be in a constant state of health.


Sirtuins are enzymes that have the ability to regulate the genes of aging3. These enzymes are dependent on NAD+ for their function as NAD+ directly activates them to switch off genes that promote aging4,5. Therefore, boosting the level of NAD+ is intimately related to longevity.


Poly-ADP-ribose polymerase-1 (PARP-1) is an enzyme that detects DNA damage and initiates DNA repair6. The function of PARP-1 is important as the accumulated replication of damaged DNA would lead to progressive functional decline in many tissues in our body which contributes to the process of aging6. For PARP-1 to exert its effect, it requires NAD+ as its sole substrate6,7. Thus, replenishment of NAD+ via supplementation is important in the prevention of damaged DNA replication and the initiation of DNA repair to protect cellular integrity7. In addition, blueberry extract is a potent antioxidant which protects cells and deters cell damage as well, complementing the actions of NAD+.


As we age, we are more inclined to get aches and pains caused by inflammation. Boswellic acids have anti-inflammatory benefit as it interferes with several protein mediators which are part of the inflammatory cascade8. Particularly, in the inhibition of 5-lipoxygenase enzyme that is responsible for the synthesis of prostaglandin E2. which is one of the inflammatory mediators that plays a decisive role in the inflammatory process9. By blocking this enzyme effectively, boswellic acids are able to reduce inflammatory reaction and relief joint pains9,10 caused by mild osteoarthritis.

How to use

Take 1-2 capsules every morning with or without food or as recommended by your physician.


Store in cool, dry place. Keep out of reach of children. Use only if bottle is sealed.


Do not take MetaboliX® Plus if you are pregnant, breastfeeding, trying to conceive or under 18 years of age.
If you have any medical conditions, please consult your physician prior to use.